What it is
Thymagen (also spelled Thymogen) is a synthetic thymic dipeptide, alpha-L-glutamyl-L-tryptophan (Glu-Trp), developed in the same Russian peptide-bioregulator program as Thymalin and Vilon. It is a low-molecular-weight immunomodulator distinct from golotimod/SCV-07 (the gamma-D-Glu-L-Trp stereoisomer with a separate literature).
Evidence boundary
Registered clinical use in Russia; small, mostly Russian literature. Research use is limited to laboratory and education contexts. Doses below are the registered/reference scale, not an endorsement.
Trial evidence
- Registered product dosing is about 100 mcg intramuscularly once daily for a short 3–10 day course; intranasal use is also registered.
Preparation and measurement
Reconstitution: 10 mg vial + 2 mL BAC = 5 mg/mL (1 U = 50 mcg).
Concentration matches.
Reference schedule
| Phase | Dose | Draw / measure | Frequency | Weekly total |
|---|---|---|---|---|
| Clinical-equivalent | 100 mcg | 2 U (0.02 mL) | Once daily, 3–10 days | 0.7 mg/week |
| Research range | 250 mcg | 5 U (0.05 mL) | 2–3× per week | 0.5–0.75 mg/week |
| Research range | 500 mcg | 10 U (0.1 mL) | 2–3× per week | 1–1.5 mg/week |
Clinical-equivalent
- Dose
- 100 mcg
- Draw / measure
- 2 U (0.02 mL)
- Frequency
- Once daily, 3–10 days
- Weekly total
- 0.7 mg/week
Research range
- Dose
- 250 mcg
- Draw / measure
- 5 U (0.05 mL)
- Frequency
- 2–3× per week
- Weekly total
- 0.5–0.75 mg/week
Research range
- Dose
- 500 mcg
- Draw / measure
- 10 U (0.1 mL)
- Frequency
- 2–3× per week
- Weekly total
- 1–1.5 mg/week
Weekly totals apply only during the active phase.
Titration rules
- Start at the clinical-equivalent 100 mcg scale for the first days.
- A 10 mg vial holds roughly a hundred clinical doses — import responsibly.
- Microgram draw volumes can be hard to read on a U-100 syringe; a 30- or 50-unit syringe improves precision.