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HGH 191AA Peptide Protocol & Dosing

Updated 1mo ago 6 min read 298+ helpful
Validity Score

Validity Score

9 Speculative
Evidence 42
Community 35
Completeness 43
Actionability 40
Coverage 80
Penalty -34

This score combines formal evidence, page completeness, calculator readiness, and community convergence.

What it is

HGH 191AA is recombinant human growth hormone, also called somatropin.

Evidence boundary

HGH 191AA is an approved drug for defined endocrine indications.

Preparation and measurement

Reconstitution: 3.33 mg vial + 3 mL BAC = 1.11 mg/mL.

Concentration matches.

Reference schedule

Reference schedule
PhaseDoseDraw / measureFrequencyWeekly total
Week 1200 mcg18.0 units (0.18 mL)5× weekly (Mon–Fri)1 mg/week
Week 2300 mcg27.0 units (0.27 mL)5× weekly (Mon–Fri)1.5 mg/week
Week 3400 mcg36.0 units (0.36 mL)5× weekly (Mon–Fri)2 mg/week
Week 4500 mcg45.0 units (0.45 mL)5× weekly (Mon–Fri)2.5 mg/week
Week 5600 mcg54.0 units (0.54 mL)5× weekly (Mon–Fri)3 mg/week
Week 6700 mcg63.0 units (0.63 mL)5× weekly (Mon–Fri)3.5 mg/week
Week 7800 mcg72.0 units (0.72 mL)5× weekly (Mon–Fri)4 mg/week
Week 8 (target)900 mcg81.0 units (0.81 mL)5× weekly (Mon–Fri)4.5 mg/week

Week 1

Dose
200 mcg
Draw / measure
18.0 units (0.18 mL)
Frequency
5× weekly (Mon–Fri)
Weekly total
1 mg/week

Week 2

Dose
300 mcg
Draw / measure
27.0 units (0.27 mL)
Frequency
5× weekly (Mon–Fri)
Weekly total
1.5 mg/week

Week 3

Dose
400 mcg
Draw / measure
36.0 units (0.36 mL)
Frequency
5× weekly (Mon–Fri)
Weekly total
2 mg/week

Week 4

Dose
500 mcg
Draw / measure
45.0 units (0.45 mL)
Frequency
5× weekly (Mon–Fri)
Weekly total
2.5 mg/week

Week 5

Dose
600 mcg
Draw / measure
54.0 units (0.54 mL)
Frequency
5× weekly (Mon–Fri)
Weekly total
3 mg/week

Week 6

Dose
700 mcg
Draw / measure
63.0 units (0.63 mL)
Frequency
5× weekly (Mon–Fri)
Weekly total
3.5 mg/week

Week 7

Dose
800 mcg
Draw / measure
72.0 units (0.72 mL)
Frequency
5× weekly (Mon–Fri)
Weekly total
4 mg/week

Week 8 (target)

Dose
900 mcg
Draw / measure
81.0 units (0.81 mL)
Frequency
5× weekly (Mon–Fri)
Weekly total
4.5 mg/week

Weekly totals apply only during the active phase.

Titration rules

  • Light/anti-aging (200 mcg/day, 5 days/week): Conservative dose. Effects subtle but established. Lowest side-effect burden.

  • Standard (400 mcg/day, 5 days/week): Common research protocol. Balance of effect and tolerability.

  • Higher (600 mcg/day, 5 days/week): Body composition / performance research. Higher side effects: edema, joint pain, glucose intolerance.

  • Timing: Evening dosing (within 1 hour of bedtime) aligns with the natural overnight GH pulse during slow-wave sleep. Avoid eating for 1–2 hours after injection — elevated insulin blunts GH efficacy.

  • Cycle structure: 6–12 months continuous (with 5-on/2-off weekly pattern). Some protocols add 4-week breaks every 12 weeks.

  • Bloodwork cadence: IGF-1 and fasting glucose every 8–12 weeks to monitor for insulin resistance development.

  • IGF-1 response in approved indications

  • Edema

  • Joint pain

  • Carpal tunnel symptoms

  • Fasting glucose / insulin resistance

  • Headache or visual changes

  • Do not treat this like a gym protocol.

Practical rules

  • Use only under endocrine care when indicated.
  • Do not treat anti-aging internet schedules as a standard.
  • Monitor glucose and IGF-1 as clinically appropriate.
  • Keep the interpretation separate from unapproved bodybuilding advice.
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