What it is
Selank is a synthetic heptapeptide from tuftsin research.
Evidence boundary
Preclinical / limited human evidence.
Trial evidence
- PMID 36322304 — Selank, a Peptide Analog of Tuftsin, Attenuates Aversive Signs of Morphine Withdrawal in Rats.
- PMID 34396551 — Sedative-Hypnotic Agents That Impact Gamma-Aminobutyric Acid Receptors: Focus on Flunitrazepam, Gamma-Hydroxybutyric Acid, Phenibut, and Selank.
- PMID 32621722 — The Influence of Selank on the Level of Cytokines Under the Conditions of “Social” Stress.
Preparation and measurement
Reconstitution: 10 mg vial + 2 mL BAC = 5 mg/mL.
Concentration matches.
Reference schedule
| Phase | Dose | Draw / measure | Frequency | Weekly total |
|---|---|---|---|---|
| Weeks 1–2 (titration) | 300 mcg | 6 U (0.06 mL) | Once daily (4 weeks on / 4 weeks off) | 2.1 mg/week |
| Weeks 3–4 (target) | 500 mcg | 10 U (0.1 mL) | Once daily (4 weeks on / 4 weeks off) | 3.5 mg/week |
Weeks 1–2 (titration)
- Dose
- 300 mcg
- Draw / measure
- 6 U (0.06 mL)
- Frequency
- Once daily (4 weeks on / 4 weeks off)
- Weekly total
- 2.1 mg/week
Weeks 3–4 (target)
- Dose
- 500 mcg
- Draw / measure
- 10 U (0.1 mL)
- Frequency
- Once daily (4 weeks on / 4 weeks off)
- Weekly total
- 3.5 mg/week
Weekly totals apply only during the active phase.
Titration rules
- Light (300 mcg, once daily): Conservative starting dose.
- Standard (600 mcg, twice daily): Common Russian clinical dose.
- Cycle structure: 4 weeks active, 2 weeks off. Some protocols extend to 6-week cycles for severe anxiety.
- Timing: Morning + early afternoon for twice-daily protocols. Avoid late-evening dosing — slight stimulant effect possible.
Cycle length and breaks
Some protocols extend to 6-week cycles for severe anxiety. The peptide does not produce dependence or sedation, making it different from benzodiazepine-class anxiolytics.
What to monitor
- Stress tolerance claims in the literature
- Nasal irritation if used intranasally
- Headache or dizziness
Practical rules
- Intranasal is the common route in the collected notes.
- Rotate sites if used sub-Q.
- Keep the language cautious.
Related protocols
Semax Peptide Protocol & DosingAdamax Peptide Protocol & DosingCerebrolysin Peptide Protocol & DosingPE-22-28 Peptide Protocol & DosingDihexa Protocol & Dosing Supply & lot verification
Availability and batch-linked COA records for Selank Peptide Protocol & Dosing are tracked with the current supplier listings.
View availability & COA →