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Longevity / Anti-Aging

Vesugen Peptide Protocol & Dosing

Updated 1mo ago 5 min read 158+ helpful Calculator
Validity Score

Validity Score

16 Speculative
Evidence 20
Community 35
Completeness 71
Actionability 80
Coverage 80
Penalty -26

This score combines formal evidence, page completeness, calculator readiness, and community convergence.

What it is

Vesugen is a short peptide bioregulator from the Khavinson literature.

Evidence boundary

Regional literature only. Do not present it as a settled vascular standard.

Trial evidence

  • PMID 26390612 — [EFFECT OF SYNTHETIC PEPTIDES ON AGING OF PATIENTS WITH CHRONIC POLYMORBIDITY AND ORGANIC BRAIN SYNDROME OF THE CENTRAL NERVOUS SYSTEM IN REMISSION].
  • PMID 25051766 — [Effect of the bioactive peptide Vesugen on the regeneration of the blood-lymph barrier in rats with experimental burn disease].
  • PMID 22808515 — [Functional and hemostatic changes in patients with diabetic retinopathy under treatment with the peptide bioregulator vesugen].
  • PMID 18546826 — [The effect of the peptide bioregulator Vesugen on endothelial function in patients with ischemic heart disease].

Preparation and measurement

Reconstitution: 20 mg vial + 3 mL BAC = 6.67 mg/mL.

Concentration matches.

Reference schedule

Reference schedule
PhaseDoseDraw / measureFrequencyWeekly total
Days 1–20 (cycle on)500 mcg7.5 U (0.075 mL)Once daily during cycle (20 days on / 4–6 months off)3.5 mg/week
Months 1–6 (cycle off)0 mcg0 U (no draw)Off0

Days 1–20 (cycle on)

Dose
500 mcg
Draw / measure
7.5 U (0.075 mL)
Frequency
Once daily during cycle (20 days on / 4–6 months off)
Weekly total
3.5 mg/week

Months 1–6 (cycle off)

Dose
0 mcg
Draw / measure
0 U (no draw)
Frequency
Off
Weekly total
0

Weekly totals apply only during the active phase.

Titration rules

  • Days 1–20 (cycle on): 500 mcg/day. Once daily during the 20-day active phase.

  • Cycle structure: 20-day active phase, 4–6 month rest. 1–2 cycles per year is standard.

  • Timing: Once daily during active phase; time of day flexible. Rotate injection sites.

  • Do not read this as stronger than the evidence supports.

  • Tolerability

  • Injection-site reactions

  • Regional protocol claims only

Practical rules

  • Rotate sites if it is being compared in notes.
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Dosing Calculator

10 mg + 2 mL BAC · suggested 500 mcg
LIVE CALCULATIONvolume / concentration / draw
RP–CALC–01
DRAW AMOUNT10 units0.1 mL · U-100
Draw 10 units, equivalent to 0.1 milliliters.
Concentration5 mg/mL
Selected dose0.5 mg (500 mcg) = 10 units
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05 Standard doses
06 Suggested doses Select a row
1 unit = 0.01 mL on a U-100 syringe. Values retain decimal precision; visual marks are not silently snapped.
07 cycle summary

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